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1

Study design of Dal-GenE, a pharmacogenetic trial targeting reduction of cardiovascular events with dalcetrapib

Tardif, Jean-Claude, DubÃ©, Marie-Pierre, Pfeffer, Marc A., Waters, David D., Koenig, Wolfgang, Maggioni, Aldo P., McMurray, John J.V., Mooser, Vincent, White, Harvey D., Heinonen, Therese, Black, Don

Journal:

American Heart Journal

Year:

2020

Language:

english

File:

PDF, 345 KB

english, 2020

2

Inhibition of cholesterol synthesis by atorvastatin in homozygous familial hypercholesterolaemia

Frederick J. Raal, Anuradha S. Pappu, D.Roger Illingworth, Gillian J. Pilcher, A.David Marais, Jean C. Firth, Maritha J. Kotze, Therese M. Heinonen, Donald M. Black

Journal:

Atherosclerosis

Year:

2000

Language:

english

File:

PDF, 121 KB

english, 2000

3

Effect of a new HMG-CoA reductase inhibitor, atorvastatin, on lipids, apolipoproteins and lipoprotein particles in patients with elevated serum cholesterol and triglyceride levels

Petar Alaupovic, Therese Heinonen, Linda Shurzinske, Donald M Black

Journal:

Atherosclerosis

Year:

1997

Language:

english

File:

PDF, 336 KB

english, 1997

4

An Evaluation of Estrogen and Atorvastatin, A New H.MGRI, in Hypercholesterolemic Postmenopausal Women

Heinonen, Therese M, Schrott, Helmut, Broyles, Frances, Shurzinske, Linda, Black, Donald M

Journal:

Year:

1996

File:

PDF, 231 KB

1996

5

New considerations in the design of clinical trials for anti-atherosclerotic drugs

Heinonen, Therese M, Black, Donald M

Journal:

Clinical Investigation

Year:

2011

Language:

english

File:

PDF, 1.07 MB

english, 2011

6

Effects of pyridoxal-5′-phosphate (MC-1) in patients undergoing high-risk coronary artery bypass surgery: Results of the MEND-CABG randomized study

Jean-Claude Tardif, Michel Carrier, David E. Kandzari, Robert Emery, Robert Cote, Therese Heinonen, Marjorie Zettler, Vic Hasselblad, Marie-Claude Guertin, Robert A. Harrington

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2007

Language:

english

File:

PDF, 137 KB

english, 2007

7

Imaging biomarkers of atherosclerosis

Noble, Stéphane, Heinonen, Therese, Tardif, Jean-Claude

Journal:

Biomarkers in Medicine

Year:

2008

Language:

english

File:

PDF, 411 KB

english, 2008

8

Coronary vasodilator reserve and Framingham risk scores in subjects at risk for coronary artery disease

Sharmila Dorbala, Alita Hassan, Therese Heinonen, Heinrich R. Schelbert, Marcelo F. Di Carli

Journal:

Journal of Nuclear Cardiology

Year:

2006

Language:

english

File:

PDF, 173 KB

english, 2006

9

Avasimibe, an ACAT inhibitor, enhances the lipid lowering effect of atorvastatin in subjects with homozygous familial hypercholesterolemia

Frederick J. Raal, A.David Marais, Ellen Klepack, Jennifer Lovalvo, Richard McLain, Therese Heinonen

Journal:

Atherosclerosis

Year:

2003

Language:

english

File:

PDF, 79 KB

english, 2003

10

Can ACAT inhibition limit the progression of atherosclerosis in patients with coronary artery disease?

Tardif, Jean-Claude, Heinonen, Therese

Journal:

Nature Clinical Practice Cardiovascular Medicine

Year:

2006

Language:

english

File:

PDF, 98 KB

english, 2006

11

Effect of Atherosclerotic Regression on Total Luminal Size of Coronary Arteries as Determined by Intravascular Ultrasound

Jean-Claude Tardif, Jean Grégoire, Philippe L. L’Allier, Reda Ibrahim, Marc-André Lavoie, Michel LeMay, Eric Cohen, Sylvie Levesque, Pierre-Frédéric Keller, Therese Heinonen, Marie-Claude Guertin

Journal:

The American Journal of Cardiology

Year:

2006

Language:

english

File:

PDF, 849 KB

english, 2006

12

Evaluation of coronary atheroma by 64-slice multidetector computed tomography: Comparison with intravascular ultrasound and angiography

Patricia Ugolini, Josephine Pressacco, Jacques Lespérance, Colin Berry, Philippe L. L’Allier, Reda Ibrahim, Jean Grégoire, Robert Ouellet, Therese Heinonen, Sylvie Levesque, Marie-Claude Guertin, Jean

Journal:

Canadian Journal of Cardiology

Year:

2009

File:

PDF, 924 KB

2009

13

Acyl coenzyme A:cholesterol acyltransferase inhibition: potential atherosclerosis therapy or springboard for other discoveries?

Heinonen, Therese M

Journal:

Expert Opinion on Investigational Drugs

Year:

2002

Language:

english

File:

PDF, 437 KB

english, 2002

14

Surrogate endpoints and emerging surrogate endpoints for risk reduction of cardiovascular disease

Crystal M Rasnake, Paula R Trumbo, Therese M Heinonen

Journal:

Nutrition Reviews

Year:

2008

Language:

english

File:

PDF, 93 KB

english, 2008

15

Design features of the Avasimibe and Progression of coronary Lesions assessed by intravascular UltraSound (A-PLUS) clinical trial

Jean-Claude Tardif, Jean Grégoire, Jacques Lespérance, Jean Lambert, Philippe L. L'Allier, Josep Rodés, Todd Anderson, John W. Blue, James Imus, Therese Heinonen

Journal:

American Heart Journal

Year:

2002

Language:

english

File:

PDF, 135 KB

english, 2002

16

Clinical Pharmacokinetics and Pharmacodynamics of Dalcetrapib

Black, Donald M., Bentley, Darren, Chapel, Sunny, Lee, Jongtae, Briggs, Emily, Heinonen, Therese

Journal:

Clinical Pharmacokinetics

Year:

2018

Language:

english

File:

PDF, 622 KB

english, 2018

17

Atherosclerosis Imaging and the Canadian Atherosclerosis Imaging Network

Tardif, Jean-Claude, Spence, J. David, Heinonen, Therese M., Moody, Alan, Pressacco, Josephine, Frayne, Richard, L'Allier, Philippe, Chow, Benjamin J.W., Friedrich, Matthias, Black, Sandra E., Fenster

Journal:

Canadian Journal of Cardiology

Year:

2013

Language:

english

File:

PDF, 258 KB

english, 2013

18

Efficacy and Safety of a New Hydroxymethylglutaryl-Coenzyme A Reductase Inhibitor, Atorvastatin, in Patients with Combined Hyperlipidemia: Comparison with Fenofibrate

Ooi, Teik C., Heinonen, Therese, Alaupovic, Petar, Davignon, Jean, Leiter, Lawrence, Lupien, Paul J., Sniderman, Allan D., Tan, Meng H., Tremblay, Gerald, Sorisky, Alexander, Shurzinske, Linda, Black,

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

1997

File:

PDF, 713 KB

1997

19

A brief review paper of the efficacy and safety of atorvastatin in early clinical trials

Rebecca G Bakker-Arkema, James Best, Rana Fayyad, Therese M Heinonen, A.David Marais, James W Nawrocki, Donald M Black

Journal:

Atherosclerosis

Year:

1997

Language:

english

File:

PDF, 225 KB

english, 1997

20

Anti-inflammatory drugs and atherosclerosis

Moubayed, Sami P, Heinonen, Therese M, Tardif, Jean-Claude

Journal:

Current Opinion in Lipidology

Year:

2007

Language:

english

File:

PDF, 119 KB

english, 2007

21

Quantitative relation between hemodynamic changes during intravenous adenosine infusion and the magnitude of coronary hyperemia: Implications for myocardial perfusion imaging

Rakesh K. Mishra, Sharmila Dorbala, Giridhar Logsetty, Alita Hassan, Therese Heinonen, Heinrich R. Schelbert, Marcelo F. Di Carli

Journal:

Journal of the American College of Cardiology

Year:

2005

Language:

english

File:

PDF, 150 KB

english, 2005

22

Inhibition of acyl coenzyme a-cholesterol acyltransferase: A possible treatment of atherosclerosis?

Therese M. Heinonen

Journal:

Current Atherosclerosis Reports

Year:

2002

Language:

english

File:

PDF, 324 KB

english, 2002

23

A winter’s tale: Report from the First Annual Canadian Biomarkers and Surrogate Endpoints Symposium

Therese Heinonen, David D. Waters, Peter Libby, Jean-Claude Tardif

Journal:

Canadian Journal of Cardiology

Year:

2009

Language:

english

File:

PDF, 803 KB

english, 2009

24

High-density lipoprotein/apolipoprotein A-I infusion therapy

Jean-Claude Tardif, Therese Heinonen, Stephane Noble

Journal:

Current Atherosclerosis Reports

Year:

2009

Language:

english

File:

PDF, 250 KB

english, 2009

25

Atorvastatin, a New HMG-CoA Reductase Inhibitor as Monotherapy and Combined With Colestipol

Heinonen, Therese M., Schrott, Helmut, McKenney, James M., Sniderman, Allan D., Broyles, Frances E., Zavoral, James H., Kivel, Frances, Black, Donald M.

Journal:

Journal of Cardiovascular Pharmacology and Therapeutics

Year:

1996

Language:

english

File:

PDF, 466 KB

english, 1996

26

Efficacy and short-term safety of a new ACAT inhibitor, avasimibe, on lipids, lipoproteins, and apolipoproteins, in patients with combined hyperlipidemia

William Insull Jr., Michael Koren, Jean Davignon, Dennis Sprecher, Helmut Schrott, Leonard M Keilson, Alan S Brown, Carlos A Dujovne, Michael H Davidson, Richard McLain, Therese Heinonen

Journal:

Atherosclerosis

Year:

2001

Language:

english

File:

PDF, 119 KB

english, 2001

27

The Role of Biomarkers in Decreasing Risk of Cardiac Toxicity after Cancer Therapy

Henri, Christine, Heinonen, Therese, Tardif, Jean-Claude

Journal:

Biomarkers in Cancer

Year:

2016

Language:

english

File:

PDF, 293 KB

english, 2016

28

Effects of the P-Selectin Antagonist Inclacumab on Myocardial Damage After Percutaneous Coronary Intervention for Non–ST-Segment Elevation Myocardial Infarction

Tardif, Jean-Claude, Tanguay, Jean-François, Wright, Scott S., Duchatelle, Valérie, Petroni, Thibaut, Grégoire, Jean C., Ibrahim, Reda, Heinonen, Therese M., Robb, Stephen, Bertrand, Olivier F., Courn

Journal:

Journal of the American College of Cardiology

Year:

2013

Language:

english

File:

PDF, 1.87 MB

english, 2013

29

Cardiovascular biomarkers and surrogate end points: key initiatives and clinical trial challenges

Heinonen, Therese M, Aamer, Maira, Marshall, Cameron, Black, Donald M, Tardif, Jean-Claude

Journal:

Expert Review of Cardiovascular Therapy

Year:

2012

Language:

english

File:

PDF, 657 KB

english, 2012

30

The lipid-lowering effects of atorvastatin, a new HMG-CoA reductase inhibitor: results of a randomized, double-masked study

Therese M. Heinonen, Evan Stein, Stuart R. Weiss, James M. McKenney, Michael Davidson, Linda Shurzinske, Donald M. Black

Journal:

Clinical Therapeutics

Year:

1996

Language:

english

File:

PDF, 640 KB

english, 1996

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